Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15987437 | 0.88 | KDM4E (0.50) | KDM4EPKML3MBTL1LMNAGAA | |
| SCHEMBL1545355 | 0.82 | KDM4E (1.00) | KDM4EPKML3MBTL1LMNAGAA | |
| SCHEMBL28828233 | 0.81 | KDM4E (0.65) | KDM4EPKML3MBTL1LMNAGAA | |
| SCHEMBL11227486 | 0.80 | TDP1 (0.50) | KDM4EPKML3MBTL1TDP1 | |
| SCHEMBL19819297 | 0.78 | KDM4E (0.92) | KDM4EPKML3MBTL1LMNAGAA | |
| SCHEMBL28474575 | 0.74 | KDM4E (0.81) | KDM4EPKML3MBTL1LMNAGAA | |
| SCHEMBL23844 | 0.73 | MAPT (0.55) | KDM4EL3MBTL1LMNAGAATDP1 | |
| SCHEMBL15647424 | 0.73 | RORC (0.45) | KDM4EPKMLMNATDP1 | |
| SCHEMBL27316158 | 0.73 | KDM4E (0.74) | KDM4EPKML3MBTL1LMNAGAA | |
| SCHEMBL23024890 | 0.73 | KDM4E (0.74) | KDM4EPKML3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573154-A | Compositions and methods for modulating short-chain dehydrogenase activity | 卡斯西部储备大学 | 2019-12-13 | — | — | CN | disclosed |