Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671402 | 0.83 | SMN1; SMN2 (0.43) | TSHRALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28339074 | 0.82 | SMN1; SMN2 (0.45) | TSHRALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28339065 | 0.80 | CALM1 (0.46) | TSHRKMT2AMAPTKDM4EMEN1 | |
| SCHEMBL1045949 | 0.79 | TSHR (0.48) | TSHRALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8659969 | 0.72 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL9638314 | 0.70 | RAB9A (0.55) | TSHRALDH1A1KMT2AAOC3CYP2C19 | |
| SCHEMBL5604665 | 0.69 | TSPO (0.57) | TSHRALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL921505 | 0.69 | NR1H2 (0.43) | TSHRALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2852601 | 0.68 | CALM1 (0.41) | TSHRALDH1A1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL28147900 | 0.68 | TSHR (0.44) | TSHRALDH1A1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021884-B | Method for efficiently synthesizing chiral 1, 2-amino alcohol by catalyzing alpha-aminoketone through Ir/f-amphox | 武汉凯特立斯科技有限公司 | 2019-12-24 | — | — | CN | claimed |
| CN-107021884-B | Method for efficiently synthesizing chiral 1, 2-amino alcohol by catalyzing alpha-aminoketone through Ir/f-amphox | 武汉凯特立斯科技有限公司 | 2019-12-24 | — | — | CN | disclosed |