Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 13/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.63 |
| ▸ | PGR | P06401 | 4/20 | 0.63 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | SHBG | P04278 | 2/20 | 0.63 |
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.58 |
| ▸ | IL6 | P05231 | 1/20 | 0.58 |
| ▸ | GLUL | P15104 | 1/20 | 0.58 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028311 | 0.94 | HIF1A (0.62) | HIF1AHSD17B10CYP2C19PGRSERPINA6 | |
| SCHEMBL3999013 | 0.92 | HIF1A (0.67) | HIF1AHSD17B10CYP2C19PGRSERPINA6 | |
| SCHEMBL138847 | 0.91 | HIF1A (0.66) | HIF1AHSD17B10CYP2C19PGRSERPINA6 | |
| SCHEMBL28809123 | 0.91 | HIF1A (0.66) | HIF1AHSD17B10CYP2C19PGRSERPINA6 | |
| SCHEMBL20553193 | 0.90 | HIF1A (0.65) | HIF1AHSD17B10CYP2C19PGRSERPINA6 | |
| SCHEMBL6001323 | 0.90 | HIF1A (0.65) | HIF1AHSD17B10CYP2C19PGRSERPINA6 | |
| SCHEMBL28715728 | 0.90 | HIF1A (0.69) | HIF1AHSD17B10CYP2C19PGRSERPINA6 | |
| SCHEMBL4426288 | 0.89 | HIF1A (0.62) | HIF1AHSD17B10CYP2C19PGRSERPINA6 | |
| SCHEMBL14931695 | 0.89 | HIF1A (0.64) | HIF1AHSD17B10CYP2C19PGRSERPINA6 | |
| SCHEMBL249836 | 0.89 | HIF1A (0.64) | HIF1AHSD17B10CYP2C19PGRSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113081991-B | Pharmaceutical dosage forms and uses thereof | 南京三迭纪医药科技有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-109431965-B | Pharmaceutical dosage forms and uses thereof | 南京三迭纪医药科技有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-113171350-A | Pharmaceutical dosage forms and uses thereof | 南京三迭纪医药科技有限公司 | 2021-07-27 | — | — | CN | disclosed |
| CN-113133980-A | Pharmaceutical dosage forms and uses thereof | 南京三迭纪医药科技有限公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-113081991-A | Pharmaceutical dosage forms and uses thereof | 南京三迭纪医药科技有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-109432039-B | Pharmaceutical dosage forms and uses thereof | Triastek, Inc. (CN) | 2021-06-22 | — | — | CN | disclosed |
| CN-106236715-B | Pharmaceutical dosage forms and uses thereof | 南京三迭纪医药科技有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-105744983-B | Device and method for sustained release of therapeutic agents of low water solubility in solubilizing agents | 纳米医学系统公司 | 2019-12-27 | — | — | CN | disclosed |