Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 13/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.67 |
| ▸ | PGR | P06401 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | SHBG | P04278 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | AR | P10275 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | TNF | P01375 | 1/20 | 0.61 |
| ▸ | IL6 | P05231 | 1/20 | 0.61 |
| ▸ | GLUL | P15104 | 1/20 | 0.61 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.61 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28809123 | 0.94 | HIF1A (0.66) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL138847 | 0.94 | HIF1A (0.66) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL20553193 | 0.93 | HIF1A (0.65) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL6001323 | 0.93 | HIF1A (0.65) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL28715728 | 0.93 | HIF1A (0.69) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL249836 | 0.92 | HIF1A (0.64) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL28553943 | 0.92 | HIF1A (0.64) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL14931695 | 0.92 | HIF1A (0.64) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL28690820 | 0.92 | HIF1A (0.64) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL29089932 | 0.92 | HIF1A (0.64) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113559105-A | Treatment of resistant acne | 维奥姆治疗有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-106163526-B | Treatment of resistant acne | 维奥姆治疗有限公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-1379197-A4 | DELIVERY OF DRUGS FROM SUSTAINED RELEASE DEVICES IMPLANTED IN MYOCARDIAL TISSUE OR IN THE PERICARDIAL SPACE | DURECT CORP (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20080095824-A1 | Delivery of drugs from sustained release devices implanted in myocardial tissue or in the pericardial space | DURECT CORPORATION | 2008-04-24 | — | — | US | disclosed |
| EP-1379197-A1 | DELIVERY OF DRUGS FROM SUSTAINED RELEASE DEVICES IMPLANTED IN MYOCARDIAL TISSUE OR IN THE PERICARDIAL SPACE | Durect Corporation (US) | 2004-01-14 | — | — | EP | disclosed |
| US-20030009145-A1 | Delivery of drugs from sustained release devices implanted in myocardial tissue or in the pericardial space | DURECT CORPORATION | 2003-01-09 | — | — | US | disclosed |
| WO-2002076344-A1 | DELIVERY OF DRUGS FROM SUSTAINED RELEASE DEVICES IMPLANTED IN MYOCARDIAL TISSUE OR IN THE PERICARDIAL SPACE | DURECT CORPORATION (US) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080095824-A1 | Delivery of drugs from sustained release devices implanted in myocardial tissue or in the pericardial space | TNNT2, TNNC1, TNNI3 | HIF1A 857/4885HSD17B10 1283/4885CYP2C19 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.