SCHEMBL4426288

SCHEMBL4426288

C=CC(=O)OC1CC(=O)C=C2CC[C@@H]3[C@H]([C@@H](O)C[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)CO)[C@]21C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 13/20 0.62
▸ HSD17B10 Q99714 6/20 0.62
▸ CYP2C19 P33261 4/20 0.62
▸ SERPINA6 P08185 4/20 0.62
▸ PGR P06401 4/20 0.62
▸ CYP3A4 P08684 4/20 0.62
▸ SMN1; SMN2 Q16637 4/20 0.62
▸ NR3C1 P04150 3/20 0.62
▸ NR3C2 P08235 3/20 0.62
▸ KMT2A Q03164 2/20 0.62
▸ SHBG P04278 2/20 0.62
▸ NFKB1 P19838 2/20 0.62
▸ MAPT P10636 2/20 0.62
▸ AR P10275 2/20 0.57
▸ ABCB11 O95342 1/20 0.57
▸ TNF P01375 1/20 0.57
▸ IL6 P05231 1/20 0.57
▸ GLUL P15104 1/20 0.57
▸ ADAM17 P78536 1/20 0.57
▸ GPBAR1 Q8TDU6 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29089932 0.94 HIF1A (0.64) HIF1AHSD17B10CYP2C19SERPINA6PGR
SCHEMBL3999013 0.91 HIF1A (0.67) HIF1AHSD17B10CYP2C19SERPINA6PGR
SCHEMBL138847 0.90 HIF1A (0.66) HIF1AHSD17B10CYP2C19SERPINA6PGR
SCHEMBL28809123 0.90 HIF1A (0.66) HIF1AHSD17B10CYP2C19SERPINA6PGR
SCHEMBL28339339 0.89 HIF1A (0.63) HIF1AHSD17B10CYP2C19SERPINA6PGR
SCHEMBL20553193 0.89 HIF1A (0.65) HIF1AHSD17B10CYP2C19SERPINA6PGR
SCHEMBL6001323 0.89 HIF1A (0.65) HIF1AHSD17B10CYP2C19SERPINA6PGR
SCHEMBL28715728 0.89 HIF1A (0.69) HIF1AHSD17B10CYP2C19SERPINA6PGR
SCHEMBL14931695 0.89 HIF1A (0.64) HIF1AHSD17B10CYP2C19SERPINA6PGR
SCHEMBL249836 0.89 HIF1A (0.64) HIF1AHSD17B10CYP2C19SERPINA6PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197963-A1 3D-PRINTING OF STRONG LIVING SCAFFOLDS NORTHWESTERN UNIVERSITY 2024-06-20 — — US claimed
US-20240197963-A1 3D-PRINTING OF STRONG LIVING SCAFFOLDS NORTHWESTERN UNIVERSITY 2024-06-20 — — US disclosed
US-20230040206-A1 Microparticle Enabled Delivery Structures, Methods of Preparing and Using Same UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2023-02-09 — — US disclosed
US-20170224632-A1 Microparticle Enabled Delivery Structures, Methods of Preparing and Using Same UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2017-08-10 — — US disclosed
EP-2010584-A2 GRAFTED POLYMERS AND USES THEREOF Interface Biologics Inc. (CA) 2009-01-07 — — EP disclosed
WO-2007148230-A2 GRAFTED POLYMERS AND USES THEREOF INTERFACE BIOLOGICS INCORPORATED (CA) 2007-12-27 — — WO disclosed
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