Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.53 |
| ▸ | PTPRC | P08575 | 2/20 | 0.52 |
| ▸ | CDC25B | P30305 | 2/20 | 0.52 |
| ▸ | PTPRF | P10586 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485068 | 0.84 | BACE1 (1.00) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL29673492 | 0.84 | BACE1 (1.00) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL25834756 | 0.83 | BACE1 (0.75) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL31423340 | 0.81 | BACE1 (1.00) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL28556962 | 0.81 | BACE1 (0.72) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL312389 | 0.81 | BACE1 (1.00) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL11048150 | 0.81 | BACE1 (0.72) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL25834777 | 0.81 | BACE1 (0.66) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL6555840 | 0.80 | BACE1 (0.75) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| Methylamine SCHEMBL3277347 | 0.79 | BACE1 (0.89) | BACE1PTPN1PTPRCCDC25BPTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113861169-A | Polysubstituted naphtho-dihydrofuran compound, preparation method and application thereof | 西华大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-110437124-B | Preparation method of indoloquinone derivative | 中国科学院成都有机化学有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-110437124-A | A kind of indoles quinone derivative and preparation method thereof | CHENGDU ORGANIC CHEM CO LTD CAS | 2019-11-12 | — | — | CN | disclosed |