Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28342705 | 0.83 | BACE1 (0.66) | BACE1MAOBPTPN1PTPRCCDC25B | |
| SCHEMBL28339368 | 0.81 | BACE1 (0.72) | BACE1MAOBPTPN1PTPRCCDC25B | |
| SCHEMBL29673492 | 0.80 | BACE1 (1.00) | BACE1MAOBPTPN1PTPRCCDC25B | |
| SCHEMBL5485068 | 0.80 | BACE1 (1.00) | BACE1MAOBPTPN1PTPRCCDC25B | |
| SCHEMBL25834756 | 0.79 | BACE1 (0.75) | BACE1MAOBPTPN1PTPRCCDC25B | |
| SCHEMBL16772151 | 0.78 | BACE1 (0.85) | BACE1PTPN1KIF11 | |
| SCHEMBL312389 | 0.77 | BACE1 (1.00) | BACE1MAOBPTPN1PTPRCCDC25B | |
| SCHEMBL28556962 | 0.77 | BACE1 (0.72) | BACE1MAOBPTPN1PTPRCCDC25B | |
| SCHEMBL11048150 | 0.77 | BACE1 (0.72) | BACE1MAOBPTPN1PTPRCCDC25B | |
| SCHEMBL31423340 | 0.77 | BACE1 (1.00) | BACE1MAOBPTPN1PTPRCCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | THE UNIVERSITY OF HONG KONG (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | THE UNIVERSITY OF HONG KONG (CN) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | NFE2L2, DUOX1, DUOX2 | BACE1 608/4885MAOB 90/4885PTPN1 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.