Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714376 | 0.87 | ALOX15 (0.47) | ALOX15KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL11841548 | 0.83 | ALOX15 (0.63) | ALOX15KDM4EKMT2ALMNAGAA | |
| SCHEMBL28339383 | 0.83 | ALOX15 (0.44) | ALOX15KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL15550185 | 0.80 | ALOX15 (0.58) | ALOX15KDM4EKMT2ALMNAGAA | |
| SCHEMBL4206934 | 0.78 | PTGDR2 (0.50) | KDM4EALDH1A1TDP1KMT2ALMNA | |
| SCHEMBL4201869 | 0.78 | PTGDR2 (0.68) | ALDH1A1TDP1KMT2ALMNAMAPK1 | |
| SCHEMBL28341850 | 0.78 | ALOX15 (0.47) | ALOX15KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL5929563 | 0.78 | ACHE (0.50) | ALOX15KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL1790082 | 0.78 | ALOX15 (0.47) | ALOX15KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL3484667 | 0.77 | LMNA (0.54) | ALOX15KDM4EALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621671-A | Benzofuran and benzothiophene derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-27 | — | — | CN | disclosed |