Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15258016 | 0.89 | HPGD (0.47) | HPGDALDH1A1GAAHDAC1HDAC6 | |
| SCHEMBL10730953 | 0.83 | HPGD (0.63) | HPGDALDH1A1GAAHDAC1HDAC6 | |
| SCHEMBL6594424 | 0.81 | HPGD (0.61) | HPGDALDH1A1GAAHDAC1HDAC6 | |
| SCHEMBL16358465 | 0.81 | HPGD (0.61) | HPGDALDH1A1GAAHDAC1HDAC6 | |
| SCHEMBL11583492 | 0.79 | HDAC1 (0.62) | HPGDALDH1A1HDAC1HDAC6NPC1 | |
| SCHEMBL27668460 | 0.78 | LMNA (0.55) | HPGDALDH1A1HDAC1HDAC6NPC1 | |
| SCHEMBL10038575 | 0.78 | OGG1 (0.57) | ALDH1A1GAAHDAC1NPC1RAB9A | |
| SCHEMBL5060811 | 0.78 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2LMNATDP1 | |
| SCHEMBL12514716 | 0.78 | ALDH1A1 (0.56) | HPGDALDH1A1HDAC1HDAC6NPC1 | |
| SCHEMBL6744163 | 0.78 | MEN1 (0.52) | GAANPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074878-B | 2, 3-dihydro-thiazolo [3,2-a ] pyridin-5-one derivatives, intermediates thereof and their use as antibacterial agents | 快尔生物技术公司 | 2019-12-24 | — | — | CN | disclosed |