SCHEMBL5060811

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15258016	0.89	HPGD (0.47)	ALDH1A1MAPTKDM4ELMNAL3MBTL1
	SCHEMBL4924405	0.81	ALDH1A1 (0.55)	ALDH1A1MAPTKDM4ELMNAL3MBTL1
	SCHEMBL4588477	0.81	ALDH1A1 (0.55)	ALDH1A1MAPTKDM4ELMNAL3MBTL1
	SCHEMBL27610435	0.81	ALDH1A1 (0.55)	ALDH1A1MAPTKDM4ELMNAL3MBTL1
	SCHEMBL27668460	0.78	LMNA (0.55)	ALDH1A1MAPTKDM4ELMNAL3MBTL1
	SCHEMBL12514716	0.78	ALDH1A1 (0.56)	ALDH1A1MAPTKDM4ERAB9ASMN1; SMN2
	SCHEMBL10038575	0.78	OGG1 (0.57)	ALDH1A1MAPTKDM4EL3MBTL1CES2
	SCHEMBL28339402	0.78	HPGD (0.63)	ALDH1A1LMNACES2CES1POLB
	SCHEMBL6744163	0.78	MEN1 (0.52)	CES2CES1POLBRAB9ASMN1; SMN2
	SCHEMBL28311338	0.78	ALDH1A1 (0.57)	ALDH1A1MAPTKDM4ELMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.