Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20295775 | 0.82 | MAP4K4 (0.35) | HTR3AADRA2AADRA2BADRA2CSLC6A4 | |
| SCHEMBL23521350 | 0.82 | ADRA1A (0.36) | ADRA1AHTR3AADRA2AADRA2BADRA2C | |
| SCHEMBL9582471 | 0.77 | MMP8 (0.35) | ADRA1AHTR3AADRA2AADRA2BADRA2C | |
| SCHEMBL12082646 | 0.76 | ADRA1A (0.37) | ADRA1AHTR3AADRA2AADRA2BADRA2C | |
| SCHEMBL14398965 | 0.74 | MMP8 (0.34) | ADRA1AHTR3AADRA2AADRA2BADRA2C | |
| SCHEMBL7541001 | 0.73 | MMP8 (0.34) | MMP8MMP3KDM4EALDH1A1GAA | |
| SCHEMBL20491468 | 0.73 | MMP8 (0.41) | ADRA1AMMP8MMP3KDM4EALDH1A1 | |
| SCHEMBL20491469 | 0.73 | MMP8 (0.41) | ADRA1AMMP8MMP3KDM4EALDH1A1 | |
| SCHEMBL9582692 | 0.73 | HTR3A (0.38) | ADRA1AHTR3AADRA2AADRA2BADRA2C | |
| SCHEMBL9582228 | 0.73 | HTR3A (0.38) | ADRA1AHTR3AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582493-B | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110582493-A | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2019-12-17 | — | — | CN | disclosed |