Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23521350 | 0.79 | ADRA1A (0.36) | MMP8MMP3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9582471 | 0.71 | MMP8 (0.35) | MMP8MMP3 | |
| Trifluoroacetic Acid SCHEMBL7532719 | 0.70 | HRH4 (0.32) | ALDH1A1AOC3SMN1; SMN2KDM4EGAA | |
| SCHEMBL9582692 | 0.68 | HTR3A (0.38) | MMP8MMP3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20491469 | 0.68 | MMP8 (0.41) | MMP8MMP3TAOK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20491468 | 0.68 | MMP8 (0.41) | MMP8MMP3TAOK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9582228 | 0.68 | HTR3A (0.38) | MMP8MMP3ALDH1A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL9582939 | 0.67 | HTR3A (0.37) | MMP8MMP3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21515924 | 0.66 | HTR3A (0.38) | MMP8MMP3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22175651 | 0.65 | AGTR2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002038153-A1 | NEW USE OF 4, 5, 6, 7-TETRAHYDROIMIDAZO-[4,5-C]PYRIDINE DERIVATIVES | BIOVITRUM AB (SE) | 2002-05-16 | — | — | WO | disclosed |