Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | VCP | P55072 | 2/20 | 0.49 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14458478 | 0.86 | ALOX5 (0.62) | MEN1KMT2AMAPTALDH1A1ALOX5 | |
| SCHEMBL12298188 | 0.83 | VCP (0.58) | MEN1KMT2AMAPTALDH1A1ALOX5 | |
| SCHEMBL28340370 | 0.83 | ALOX5 (0.69) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL12298123 | 0.81 | RAB9A (0.62) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL12298371 | 0.81 | KDM1A (0.53) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL12297190 | 0.80 | ALOX5 (0.74) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL12298201 | 0.80 | NPC1 (0.52) | MEN1KMT2AMAPTALDH1A1ALOX5 | |
| SCHEMBL7111034 | 0.78 | MEN1 (0.66) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL12298095 | 0.77 | ALOX5 (0.66) | MEN1KMT2AMAPTALDH1A1ALOX5 | |
| SCHEMBL12298177 | 0.77 | ALOX5 (0.48) | MEN1KMT2AMAPTALOX5KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590785-B | Aminothiazole compound, preparation method thereof and application of aminothiazole compound in resisting enterovirus 71 | 武汉大学 | 2021-02-02 | — | — | CN | disclosed |
| CN-110590785-A | Aminothiazole compound, preparation method thereof and application of aminothiazole compound in resisting enterovirus 71 | 武汉大学 | 2019-12-20 | — | — | CN | disclosed |