SCHEMBL28340808

SCHEMBL28340808

C=CC(CCCCC)OC(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.44
ZDHHC7 Q9NXF8 1/20 0.43
PLA2G2C Q5R387 1/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 1/20 0.38
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
FAAH O00519 4/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
PLA2G2A P14555 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GPR84 Q9NQS5 3/20 0.36
FFAR1 O14842 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12514261 0.85 LMNA (0.46) ABCB1ZDHHC7PLA2G2CCA1FAAH
SCHEMBL6899683 0.85 ABCB1 (0.41) ABCB1ZDHHC7PLA2G2CMEN1HPGD
SCHEMBL15689848 0.84 FAAH (0.39) ABCB1ZDHHC7CA1FAAHALDH1A1
SCHEMBL111270 0.84 FAAH (0.39) ABCB1ZDHHC7CA1FAAHALDH1A1
SCHEMBL15645172 0.84 FAAH (0.39) ABCB1ZDHHC7CA1FAAHALDH1A1
SCHEMBL6419954 0.83 CTSK (0.35) ABCB1PLA2G2CCA2
SCHEMBL6898457 0.82 ABCB1 (0.43) ABCB1ZDHHC7PLA2G2CCA1FAAH
SCHEMBL12120759 0.82 ABCB1 (0.43) ABCB1ZDHHC7PLA2G2CCA1FAAH
SCHEMBL10576490 0.82 GPR84 (0.44) ABCB1ZDHHC7MEN1KMT2AZDHHC20
SCHEMBL4350901 0.82 ABCB1 (0.44) ABCB1ZDHHC7CA1HPGDFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627717-B Branched 1, 4-diene amide derivative and synthesis method thereof 杭州师范大学 2021-01-26 CN disclosed
CN-110627717-A Branched 1, 4-diene amide derivative and synthesis method thereof 杭州师范大学 2019-12-31 CN disclosed