Benzene

Benzene

SCHEMBL28343003

O=C(C(=O)c1ccccc1-c1ccc(-c2ccccc2)cc1)c1ccccc1.c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.55
CES2 O00748 6/20 0.54
CES1 P23141 5/20 0.54
SMN1; SMN2 Q16637 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CHRNB2 P17787 2/20 0.49
CHRNB4 P30926 2/20 0.49
CHRNA3 P32297 2/20 0.49
CHRNA4 P43681 2/20 0.49
CDC25B P30305 1/20 0.47
ATM Q13315 1/20 0.47
HNF4A P41235 1/20 0.47
TSHR P16473 1/20 0.46
RECQL P46063 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28340553 1.00 BCAT2 (0.55) BCAT2CES2CES1SMN1; SMN2MEN1
SCHEMBL27676197 0.96 BCAT2 (0.59) BCAT2CES2CES1SMN1; SMN2MEN1
SCHEMBL30277841 0.96 BCAT2 (0.59) BCAT2CES2CES1SMN1; SMN2MEN1
SCHEMBL3806467 0.88 BCAT2 (0.68) BCAT2SMN1; SMN2MEN1KMT2ACHRNB2
SCHEMBL981885 0.87 CES2 (0.63) BCAT2CES2CES1SMN1; SMN2MEN1
SCHEMBL28864516 0.87 CES2 (0.63) BCAT2CES2CES1SMN1; SMN2MEN1
SCHEMBL29972427 0.86 CES2 (0.67) CES2CES1TSHRRAB9AALDH1A1
SCHEMBL28987668 0.84 CES2 (0.45) BCAT2CES2CES1SMN1; SMN2MEN1
SCHEMBL16353485 0.84 CDC25B (0.49) BCAT2CES2CES1SMN1; SMN2MEN1
SCHEMBL7485120 0.83 CES2 (0.67) CES2CES1SMN1; SMN2KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110628021-B Side chain type sulfonated polyquinoxaline and proton exchange membrane thereof 北京理工大学 2022-03-18 CN disclosed
CN-110628021-A Side chain type sulfonated polyquinoxaline and proton exchange membrane thereof 北京理工大学 2019-12-31 CN disclosed