Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 8/20 | 0.63 |
| ▸ | CES1 | P23141 | 8/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL28340553 | 0.87 | BCAT2 (0.55) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| Benzene SCHEMBL28343003 | 0.87 | BCAT2 (0.55) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30277841 | 0.87 | BCAT2 (0.59) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27676197 | 0.87 | BCAT2 (0.59) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8562483 | 0.86 | KMT2A (0.49) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5693606 | 0.84 | AKR1C3 (0.61) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28864516 | 0.83 | CES2 (0.63) | CES2CES1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7485120 | 0.82 | CES2 (0.67) | CES2CES1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL31402608 | 0.82 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2AKR1C3BCAT2 | |
| SCHEMBL372 | 0.82 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2AKR1C3BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668015-B1 | CUCURBITURIL ASSEMBLY AND USES THEREOF | TECHNION RES & DEV FOUNDATION (IL) | 2013-08-21 | — | — | EP | disclosed |
| US-7875713-B2 | affinity pairs that can be efficiently utilized without being limited by factors such as chemical versatility, stability, irreversibility; for affinity chromatography, affinity labeling, immobilization, bioconjugation, immunohistochemical staining, flow cytometry, in situ hybridization, genetic mapping | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2011-01-25 | — | — | US | disclosed |
| US-20060292570-A1 | Novel synthetic binding pairs and uses thereof | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2006-12-28 | — | — | US | disclosed |
| EP-1668015-A2 | SYNTHETIC BINDING PAIRS COMPRISING CUCURBITURIL DERIVATIVES AND POLYAMMONIUM COMPOUNDS AND USES THEREOF | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. (IL) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005023816-A2 | SYNTHETIC BINDING PAIRS COMPRISING CUCURBITURIL DERIVATIVES AND POLYAMMONIUM COMPOUDS AND USES THEREOF | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060292570-A1 | Novel synthetic binding pairs and uses thereof | DBNL, GEMIN5, PICALM | CES2 1634/4885CES1 4527/4885KMT2A 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.