SCHEMBL28987668

SCHEMBL28987668

O=Cc1ccc(-c2ccccc2C(=O)C(=O)c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.45
CES1 P23141 5/20 0.45
BCAT2 O15382 1/20 0.43
ALDH1A1 P00352 5/20 0.43
DRD1 P21728 3/20 0.43
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42
DRD5 P21918 1/20 0.42
DRD3 P35462 1/20 0.42
CYP2A6 P11509 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
LTB4R2 Q9NPC1 1/20 0.39
UNG P13051 1/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10586919 0.85 ALDH1A1 (0.51) BCAT2ALDH1A1DRD1DRD2DRD4
Benzene SCHEMBL28343003 0.84 BCAT2 (0.55) CES2CES1BCAT2ALDH1A1MEN1
Biphenyl SCHEMBL28340553 0.84 BCAT2 (0.55) CES2CES1BCAT2ALDH1A1MEN1
SCHEMBL27676197 0.84 BCAT2 (0.59) CES2CES1BCAT2ALDH1A1MEN1
SCHEMBL30277841 0.84 BCAT2 (0.59) CES2CES1BCAT2ALDH1A1MEN1
SCHEMBL9597954 0.83 KDM4E (0.50) BCAT2ALDH1A1DRD1DRD2DRD4
SCHEMBL29951779 0.83 KDM4E (0.50) BCAT2ALDH1A1DRD1DRD2DRD4
SCHEMBL28271046 0.80 CES2 (0.68) CES2CES1ALDH1A1CYP2A6KMT2A
SCHEMBL981885 0.80 CES2 (0.63) CES2CES1BCAT2MEN1KMT2A
SCHEMBL28864516 0.80 CES2 (0.63) CES2CES1BCAT2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115975138-A Microporous covalent organic framework material based on quinoxaline and imine bond connection and preparation method thereof 北京理工大学 2023-04-18 CN claimed
CN-115975138-A Microporous covalent organic framework material based on quinoxaline and imine bond connection and preparation method thereof 北京理工大学 2023-04-18 CN disclosed
CN-115975138-A Microporous covalent organic framework material based on quinoxaline and imine bond connection and preparation method thereof 北京理工大学 2023-04-18 CN disclosed