SCHEMBL28343103

SCHEMBL28343103

CCOC(OCC)c1ccccc1-c1ccccc1Br

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
MAPK1 P28482 2/20 0.36
CDC25B P30305 2/20 0.34
PTPRC P08575 2/20 0.34
PTGS2 P35354 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 4/20 0.31
LMNA P02545 3/20 0.31
MAPT P10636 3/20 0.31
HPGD P15428 3/20 0.31
KDM4E B2RXH2 2/20 0.31
CYP3A4 P08684 2/20 0.31
ALOX15 P16050 2/20 0.31
CYP2C19 P33261 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MAP2K7 O14733 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933759 0.85 IDO1 (0.39) ALDH1A1PTGS2L3MBTL1IDO1TDO2
SCHEMBL29896649 0.85 IDO1 (0.39) ALDH1A1PTGS2L3MBTL1IDO1TDO2
SCHEMBL28343099 0.79 ALDH1A1 (0.40) ALDH1A1MAPK1CDC25BIDO1TDO2
SCHEMBL20278735 0.79 MAPT (0.41) ALDH1A1MAPK1L3MBTL1IDO1MEN1
SCHEMBL8651248 0.78 L3MBTL1 (0.38) ALDH1A1MAPK1CDC25BPTPRCPTGS2
SCHEMBL28343102 0.75 ALDH1A1 (0.37) ALDH1A1MAPK1CDC25BPTPRCPTGS2
Ether SCHEMBL2803999 0.74 ALDH1A1 (0.46) ALDH1A1MAPK1L3MBTL1IDO1TDP1
SCHEMBL4427313 0.72 CA1 (0.46) ALDH1A1MAPK1L3MBTL1IDO1LMNA
SCHEMBL22824151 0.72 HTT (0.40) ALDH1A1L3MBTL1IDO1TDO2TDP1
SCHEMBL898540 0.71 ESR1 (0.50) ALDH1A1PTGS2L3MBTL1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627831-A Bibiaryl acetal phosphines, their preparation and use in coupling reactions 东莞市均成高新材料有限公司 2019-12-31 CN disclosed