Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.58 |
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28881130 | 0.73 | KDM4E (0.57) | MAOAMAOBKIF11KDM4EKMT2A | |
| SCHEMBL28343220 | 0.73 | MAOB (0.59) | MAOAMAOBCA1CA2KDM4E | |
| SCHEMBL28346117 | 0.72 | KDM4E (0.53) | MAOAMAOBKIF11KDM4EKMT2A | |
| SCHEMBL7044798 | 0.71 | HDAC1 (0.64) | — | |
| SCHEMBL7291202 | 0.68 | MTNR1A (0.61) | KDM4EKMT2A | |
| Methylamine SCHEMBL6594130 | 0.68 | ALDH1A1 (0.58) | KMT2ARAB9A | |
| SCHEMBL6328945 | 0.68 | HPGD (0.60) | KMT2ANPC1RAB9A | |
| SCHEMBL28259674 | 0.67 | MAOA (0.55) | MAOAMAOBCA1CA2 | |
| SCHEMBL3313199 | 0.67 | KDM4E (0.75) | MAOAMAOBKDM4EKMT2A | |
| SCHEMBL203998 | 0.67 | PARP1 (0.58) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | claimed |
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | disclosed |