Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28881130 | 0.79 | KDM4E (0.57) | KDM4EGAAKIF11MEN1KMT2A | |
| SCHEMBL28343222 | 0.73 | KDM4E (0.49) | KDM4EGAAKIF11MEN1KMT2A | |
| SCHEMBL28343225 | 0.72 | MAOA (0.58) | KDM4EKIF11KMT2AMAOAMAOB | |
| SCHEMBL3622572 | 0.67 | KIF11 (0.71) | TERTKIF11 | |
| SCHEMBL14132769 | 0.67 | KDM4E (0.83) | KDM4EGAAMEN1KMT2A | |
| SCHEMBL30590298 | 0.66 | MEN1 (0.59) | KDM4EGAAMEN1KMT2AMAOA | |
| SCHEMBL30590318 | 0.66 | MEN1 (0.59) | KDM4EGAAMEN1KMT2AMAOA | |
| SCHEMBL13986558 | 0.66 | MEN1 (0.58) | MEN1KMT2A | |
| SCHEMBL5318251 | 0.64 | LMNA (0.65) | — | |
| SCHEMBL3313199 | 0.64 | KDM4E (0.75) | KDM4EKMT2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | claimed |
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | disclosed |