Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18378463 | 0.83 | TSHR (0.48) | POLBTSHRTRPM8SMN1; SMN2GAA | |
| SCHEMBL28343287 | 0.82 | GAA (0.49) | POLBTSHRTRPM8SMN1; SMN2GAA | |
| SCHEMBL18186741 | 0.82 | POLB (0.47) | POLBTSHRTRPM8SMN1; SMN2GAA | |
| SCHEMBL10697750 | 0.81 | MEN1 (0.53) | TSHRTRPM8SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7448120 | 0.80 | SMN1; SMN2 (0.53) | POLBTSHRTRPM8SMN1; SMN2GAA | |
| SCHEMBL1694615 | 0.80 | LMNA (0.42) | POLBTSHRTRPM8SMN1; SMN2GAA | |
| SCHEMBL5508940 | 0.79 | POLB (0.60) | POLBTSHRTRPM8SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL29361741 | 0.78 | RAB9A (0.47) | TSHRGAAKMT2ALMNA | |
| SCHEMBL2562392 | 0.78 | POLB (0.51) | POLBTSHRTRPM8SMN1; SMN2GAA | |
| SCHEMBL27600746 | 0.77 | TSHR (0.43) | POLBTSHRSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730570-A1 | METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-09-11 | — | — | EP | disclosed |