Formamide

Formamide

SCHEMBL28343999

CC1CC(CCc2ccccc2)CCN1C.NC=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.47
PRMT6 Q96LA8 1/20 0.47
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43
CTSS P25774 1/20 0.43
CTSK P43235 1/20 0.43
CTSC P53634 1/20 0.43
NR3C1 P04150 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27570826 0.79 CARM1 (0.52) CARM1PRMT6MAOAMAOBCTSL
Formamide SCHEMBL27459446 0.72 DRD2 (0.42) CARM1PRMT6
SCHEMBL10071184 0.72 CARM1 (0.65) CARM1PRMT6MAOAMAOBCTSL
SCHEMBL27589295 0.71 HRH3 (0.48) CARM1PRMT6
Formic Acid SCHEMBL27732454 0.71 MAOA (0.51) CARM1PRMT6MAOAMAOBCTSL
SCHEMBL12049826 0.70 CTSS (0.62) CARM1PRMT6MAOAMAOBCTSL
SCHEMBL21535761 0.70 CTSS (0.62) CARM1PRMT6MAOAMAOBCTSL
SCHEMBL27843918 0.70 CARM1 (0.62) CARM1PRMT6MAOAMAOB
SCHEMBL11209800 0.69 MAOA (0.59) CARM1PRMT6MAOAMAOBCTSL
Formamide SCHEMBL11158316 0.69 MC4R (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110662541-B Polycyclic amines as opioid receptor modulators 王晓冬 2023-02-10 CN disclosed
CN-110662541-A Polycyclic amines as opioid receptor modulators 王晓冬 2020-01-07 CN disclosed