Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435718 | 0.89 | ALDH1A1 (0.57) | ALDH1A1LMNAHSD17B10CYP2C19KMT2A | |
| SCHEMBL28428637 | 0.86 | ALDH1A1 (0.49) | ALDH1A1LMNAHSD17B10CYP2C19KDM4E | |
| SCHEMBL28540631 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10CYP2C19KDM4E | |
| SCHEMBL28428728 | 0.86 | ALDH1A1 (0.44) | MAPK10ALDH1A1LMNAHSD17B10CYP2C19 | |
| SCHEMBL28426597 | 0.86 | ALDH1A1 (0.48) | MAPK10ALDH1A1LMNAHSD17B10CYP2C19 | |
| SCHEMBL28549191 | 0.84 | MAPT (0.44) | RECQLMAPK10ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28553092 | 0.84 | L3MBTL1 (0.55) | ALDH1A1HSD17B10CYP2C19MEN1KMT2A | |
| SCHEMBL28540690 | 0.84 | KIF11 (0.50) | MAPK10ALDH1A1LMNAHSD17B10CYP2C19 | |
| SCHEMBL29284815 | 0.82 | ALDH1A1 (0.51) | ALDH1A1LMNAHSD17B10CYP2C19POLB | |
| SCHEMBL28281378 | 0.82 | MEN1 (0.44) | ALDH1A1LMNAHSD17B10CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526855-B | Preparation method of 3-nitroso substituted indole derivative | 郑州大学 | 2020-11-27 | — | — | CN | disclosed |
| CN-109535061-B | 3-nitrosoindole derivative and preparation method thereof | 苏州大学 | 2020-07-14 | — | — | CN | disclosed |
| CN-110526855-A | A kind of preparation method for the indole derivatives that 3- nitroso replaces | UNIV ZHENGZHOU | 2019-12-03 | — | — | CN | disclosed |