Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28428637 | 0.85 | ALDH1A1 (0.49) | MAPTALDH1A1LMNAHSD17B10CYP2C19 | |
| SCHEMBL1435718 | 0.85 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAHSD17B10CYP2C19 | |
| SCHEMBL28344370 | 0.84 | RECQL (0.48) | MAPTMAPK10ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28544781 | 0.83 | KIF11 (0.48) | KIF11MAPTMAPK10ALDH1A1LMNA | |
| SCHEMBL28426597 | 0.82 | ALDH1A1 (0.48) | MAPTMAPK10ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28428728 | 0.82 | ALDH1A1 (0.44) | MAPTMAPK10ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28540631 | 0.82 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAHSD17B10CYP2C19 | |
| SCHEMBL28553092 | 0.80 | L3MBTL1 (0.55) | MAPTALDH1A1HSD17B10CYP2C19HTT | |
| SCHEMBL28549830 | 0.77 | ALDH1A1 (0.39) | MAPTMAPK10ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28539176 | 0.75 | CCNB2 (0.42) | MAPTMAPK10ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526855-B | Preparation method of 3-nitroso substituted indole derivative | 郑州大学 | 2020-11-27 | — | — | CN | disclosed |