Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755703 | 0.86 | CYP3A4 (0.44) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL20468614 | 0.76 | CYP19A1 (0.39) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL16772630 | 0.76 | MAP3K14 (0.30) | — | |
| SCHEMBL16775285 | 0.72 | TP53 (0.42) | CYP19A1SCN9AGAAKDM4EALDH1A1 | |
| SCHEMBL31372096 | 0.72 | DRD2 (0.39) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL31371933 | 0.72 | CA2 (0.40) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL9042535 | 0.72 | SIGMAR1 (0.47) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL28347428 | 0.71 | DRD2 (0.37) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL31371949 | 0.71 | DRD2 (0.44) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL4641423 | 0.71 | DRD2 (0.41) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110664816-A | SECA inhibitors and methods of making and using the same | 佐治亚州立大学研究基金会公司 | 2020-01-10 | — | — | CN | disclosed |