Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232945 | 0.89 | HMGB1 (0.43) | GRIK1PTPN2PTPN1PTPRCAXL | |
| SCHEMBL5323308 | 0.84 | LTB4R (0.41) | LTB4RGRIK1PTPN2PTPN1PTPRC | |
| SCHEMBL27675976 | 0.82 | GPR35 (0.49) | LTB4RAXLLMNAABCC1 | |
| SCHEMBL4732259 | 0.81 | PTPN2 (0.43) | GRIK1PTPN2PTPN1PTPRCAXL | |
| SCHEMBL4371004 | 0.81 | LTB4R (0.44) | LTB4RPTPN2PTPN1PTPRCAXL | |
| SCHEMBL30544 | 0.81 | GPR35 (0.55) | LTB4RABCC1 | |
| SCHEMBL23142270 | 0.80 | KMT2A (0.49) | TSHRKMT2A | |
| SCHEMBL4196235 | 0.79 | PTPN1 (0.42) | LTB4RGRIK1PTPN2PTPN1PTPRC | |
| SCHEMBL8516407 | 0.79 | GPR35 (0.57) | LTB4R | |
| SCHEMBL17353545 | 0.79 | GPR35 (0.57) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511220-A | As the para diaminobenzene derivative of potassium channel modulating agents, preparation method and its application in medicine | SHANGHAI ZHIMENG PHARMACEUTICAL TECH CO LTD | 2019-11-29 | — | — | CN | disclosed |