SCHEMBL4371004

SCHEMBL4371004

O=C(O)c1sccc1CCCCCCCCCCCO

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 9/20 0.44
GPR35 Q9HC97 1/20 0.41
PTPN2 P17706 1/20 0.38
PTPN1 P18031 1/20 0.38
PTPRC P08575 2/20 0.37
AXL P30530 1/20 0.37
LMNA P02545 1/20 0.37
ABCC1 P33527 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KMT2A Q03164 1/20 0.36
PTPRG P23470 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5323308 0.93 LTB4R (0.41) LTB4RGPR35PTPN2PTPN1PTPRC
SCHEMBL4196235 0.85 PTPN1 (0.42) LTB4RGPR35PTPN2PTPN1PTPRC
SCHEMBL7474906 0.85 GPR35 (0.57) LTB4RGPR35
SCHEMBL17353545 0.85 GPR35 (0.57) LTB4RGPR35
SCHEMBL4436638 0.85 GPR35 (0.57) LTB4RGPR35
SCHEMBL8516407 0.85 GPR35 (0.57) LTB4RGPR35
SCHEMBL30544 0.83 GPR35 (0.55) LTB4RGPR35ABCC1
SCHEMBL27675976 0.81 GPR35 (0.49) LTB4RGPR35AXLLMNAABCC1
SCHEMBL28345653 0.81 TSHR (0.41) LTB4RPTPN2PTPN1PTPRCAXL
SCHEMBL28587372 0.78 LTB4R (0.62) LTB4RPTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009107902-A1 BRUSH POLYETHER-BASED POLYMERS, PREPARATION METHODS THEREOF AND CHEMICAL SENSORS COMPRISING THE POLYMERS POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2009-09-03 WO disclosed
WO-2008093905-A1 BIOCOMPATIBLE ALIPHATIC BRUSH POLYMERS AND MANUFACTURING METHODS THEREOF POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2008-08-07 WO disclosed