Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16375063 | 0.85 | ROCK1 (0.38) | ROCK1 | |
| SCHEMBL22497768 | 0.76 | ROCK1 (0.39) | ROCK1LPLLIPG | |
| SCHEMBL12502368 | 0.74 | NOTUM (0.43) | ROCK1F2F11PRSS1PRSS2 | |
| SCHEMBL27212326 | 0.72 | NOTUM (0.42) | ROCK1F2F11PRSS1PRSS2 | |
| SCHEMBL27157750 | 0.72 | ROCK1 (0.36) | ROCK1LPLLIPG | |
| SCHEMBL20271077 | 0.70 | ROCK1 (0.41) | ROCK1F2F11PRSS1PRSS2 | |
| SCHEMBL16195920 | 0.69 | CYP11B2 (0.50) | — | |
| SCHEMBL1477653 | 0.69 | ROCK1 (0.37) | ROCK1LPLLIPG | |
| SCHEMBL6127173 | 0.69 | LPL (0.41) | ROCK1F11LPLLIPG | |
| SCHEMBL28347181 | 0.68 | SMN1; SMN2 (0.33) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698481-A | Heteroaryl pyridone and aza-pyridone amide compounds | 豪夫迈·罗氏有限公司 | 2020-01-17 | — | — | CN | disclosed |