Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 3/20 | 0.32 |
| ▸ | FPR2 | P25090 | 3/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16375061 | 0.83 | GPR119 (0.37) | — | |
| SCHEMBL16375196 | 0.80 | MEN1 (0.38) | SMN1; SMN2MEN1KMT2AFPR1FPR2 | |
| SCHEMBL16367610 | 0.78 | HSD11B1 (0.35) | FPR1FPR2 | |
| SCHEMBL26922623 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL16346678 | 0.69 | GPR52 (0.39) | FPR1FPR2 | |
| SCHEMBL28347176 | 0.68 | ROCK1 (0.42) | NOTUM | |
| SCHEMBL17542683 | 0.64 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL20639114 | 0.64 | TAS2R14 (0.39) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL16375060 | 0.63 | ESR2 (0.46) | MAPTNOTUM | |
| SCHEMBL16375062 | 0.62 | ABHD6 (0.38) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698481-A | Heteroaryl pyridone and aza-pyridone amide compounds | 豪夫迈·罗氏有限公司 | 2020-01-17 | — | — | CN | disclosed |