Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889162 | 0.73 | GPR3 (0.44) | GPR3GAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23520161 | 0.70 | GPR3 (0.42) | GPR3GAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL18833313 | 0.67 | PDGFRB (0.40) | GPR3GAAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL28735591 | 0.66 | KDM4E (0.50) | GPR3GAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29403090 | 0.65 | PDGFRB (0.64) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL993337 | 0.65 | PDGFRB (0.64) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7940617 | 0.63 | NOS2 (0.42) | GPR3GAAKDM4EALDH1A1PDGFRB | |
| SCHEMBL10540887 | 0.63 | TSHR (0.47) | KDM4EALDH1A1PRCPHPGDTSHR | |
| Hydrochloric Acid SCHEMBL8378388 | 0.62 | NOS2 (0.41) | GPR3KDM4EALDH1A1PDGFRBMEN1 | |
| SCHEMBL5175484 | 0.60 | TTR (0.50) | KDM4EALDH1A1HPGDLMNATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526855-B | Preparation method of 3-nitroso substituted indole derivative | 郑州大学 | 2020-11-27 | — | — | CN | disclosed |
| CN-110526855-A | A kind of preparation method for the indole derivatives that 3- nitroso replaces | UNIV ZHENGZHOU | 2019-12-03 | — | — | CN | disclosed |