Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21736978 | 0.76 | ALDH1A1 (0.38) | CYP17A1CYP11B1CYP11B2ALDH1A1RAB9A | |
| SCHEMBL18306474 | 0.76 | TUBB1 (0.34) | TDO2CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL3977710 | 0.75 | — | — | |
| SCHEMBL28292563 | 0.74 | GAA (0.42) | TDO2CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL21819564 | 0.74 | L3MBTL1 (0.39) | TDO2CYP17A1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL30231238 | 0.74 | L3MBTL1 (0.39) | TDO2CYP17A1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL22660811 | 0.74 | POLB (0.34) | CYP17A1CYP11B1CYP11B2ALDH1A1RAB9A | |
| SCHEMBL18114233 | 0.74 | TDO2 (0.35) | TDO2CYP3A4ALDH1A1RAB9AKDM4E | |
| SCHEMBL24656021 | 0.71 | BRAF (0.33) | TDO2CYP11B1CYP11B2ALDH1A1BRAF | |
| SCHEMBL20844135 | 0.71 | P2RX3 (0.36) | CYP17A1CYP11B1CYP11B2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024216164-A1 | N2-((5-HYDROXY)-2-PYRIDYL)-PYRIDINE-2,4-DIAMINE DERIVATIVES AS EHMT1/2 MODULATORS FOR THE TREATMENT OF CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |
| CN-110669001-B | Synthetic method of 3-fluoro-4-halogeno-5-methoxypyridine | 阿里生物新材料（常州）有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-110669001-A | Synthetic method of 3-fluoro-4-halogeno-5-methoxypyridine | 阿里生物新材料（常州）有限公司 | 2020-01-10 | — | — | CN | disclosed |