Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pimelic Acid SCHEMBL30288553 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL30302268 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22GPR84 | |
| Glutarate SCHEMBL28360836 | 0.95 | SLC22A6 (0.55) | LMNATSHRNFKB1PMP22GPR84 | |
| Succinic Acid SCHEMBL30288581 | 0.90 | LMNA (0.50) | LMNATSHRNFKB1PMP22GPR84 | |
| Stearic Acid SCHEMBL26635447 | 0.88 | GPR84 (0.65) | LMNATSHRGPR84FFAR1FFAR4 | |
| Mercaptopropionic Acid SCHEMBL15379870 | 0.81 | ACE (0.44) | LMNACAMK2AFOLH1KDM5AKDM7A | |
| Bicarbonate SCHEMBL5274866 | 0.81 | PLG (0.40) | LMNATSHRPMP22CYP2D6TDP1 | |
| SCHEMBL3847073 | 0.80 | CYP1A2 (0.52) | LMNAACHE | |
| SCHEMBL11329424 | 0.80 | KDM5A (0.61) | LMNATSHRNFKB1PMP22GPR84 | |
| E388 SCHEMBL3950655 | 0.79 | LMNA (0.61) | LMNATSHRFFAR4CAMK2AKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116814028-A | Heat-conducting damping rubber pad for new energy battery and preparation method | 江苏迈云达科技有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-112194890-A | Polyurethane material and preparation method thereof | 南通濠泰化工产品有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-107573835-B | Lens color-changing coating and color-changing lens | 东莞粤恒光学有限公司 | 2020-01-14 | — | — | CN | claimed |
| CN-118874253-A | Modified polyurethane three-proofing paint preparation system with UV indication function | 深圳爱邦新材料技术有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-116814028-A | Heat-conducting damping rubber pad for new energy battery and preparation method | 江苏迈云达科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-109791381-B | Electrophotographic photoreceptor, and electrophotographic process cartridge and image forming apparatus containing the same | 三菱化学株式会社 | 2023-03-10 | — | — | CN | disclosed |
| CN-112194890-A | Polyurethane material and preparation method thereof | 南通濠泰化工产品有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-112194890-A | Polyurethane material and preparation method thereof | 南通濠泰化工产品有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-107573835-B | Lens color-changing coating and color-changing lens | 东莞粤恒光学有限公司 | 2020-01-14 | — | — | CN | disclosed |