Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutarate SCHEMBL28360836 | 0.90 | SLC22A6 (0.55) | LMNAALDH1A1CAMK2ASLC22A6PHF8 | |
| Adipic Acid SCHEMBL28348294 | 0.90 | LMNA (0.55) | LMNAALDH1A1CAMK2ASLC22A6PHF8 | |
| Pimelic Acid SCHEMBL30288553 | 0.87 | TSHR (0.57) | LMNAALDH1A1OR51E2CAMK2ASLC22A6 | |
| SCHEMBL30302268 | 0.87 | TSHR (0.57) | LMNAALDH1A1OR51E2CAMK2ASLC22A6 | |
| Mercaptopropionic Acid SCHEMBL15379870 | 0.85 | ACE (0.44) | LMNAEGLN1ALKBH5SUCNR1CAMK2A | |
| Bicarbonate SCHEMBL5274866 | 0.85 | PLG (0.40) | LMNATSHRPMP22PLGPLAT | |
| E388 SCHEMBL3950655 | 0.84 | LMNA (0.61) | LMNAEGLN1ALKBH5SUCNR1ALDH1A1 | |
| Malonic Acid SCHEMBL30288560 | 0.83 | LDHA (0.50) | LMNAALDH1A1PHF8KDM2AKDM5A | |
| Thioglycolic Acid SCHEMBL97834 | 0.81 | ANPEP (0.39) | LMNAGABRR1PLGPLATESR1 | |
| SCHEMBL2708681 | 0.81 | ANPEP (0.48) | LMNAALDH1A1MAPTGABRR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109791381-B | Electrophotographic photoreceptor, and electrophotographic process cartridge and image forming apparatus containing the same | 三菱化学株式会社 | 2023-03-10 | — | — | CN | disclosed |