Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | MMP8 | P22894 | 4/20 | 0.44 |
| ▸ | MMP12 | P39900 | 4/20 | 0.44 |
| ▸ | MMP13 | P45452 | 4/20 | 0.44 |
| ▸ | MMP14 | P50281 | 4/20 | 0.44 |
| ▸ | MMP16 | P51512 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29700218 | 1.00 | HNF4A (0.49) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL9246392 | 0.91 | HDAC4 (0.53) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL12903976 | 0.85 | HTR6 (0.57) | HTR6POLBGAAGFERMMP1 | |
| SCHEMBL9242466 | 0.83 | HTR6 (0.55) | HTR6POLBGAAGFERMMP1 | |
| SCHEMBL8368643 | 0.81 | HDAC4 (0.52) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL1028866 | 0.80 | POLB (0.49) | HTR6POLBGAAGFERMMP1 | |
| SCHEMBL29700169 | 0.80 | PTGS2 (0.52) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL27723038 | 0.80 | HTR6 (0.48) | HTR6POLBGAAGFERMMP1 | |
| SCHEMBL9793435 | 0.80 | HTR6 (0.48) | HTR6POLBGAAGFERMMP1 | |
| SCHEMBL139251 | 0.79 | POLB (0.55) | HTR6POLBGAAGFERMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110683940-B | Method for converting dibenzo [ c, e ] [1,2] oxathiane-6-oxide compound | 中国科学院成都生物研究所 | 2022-07-01 | — | — | CN | disclosed |
| CN-110683940-A | Method for converting dibenzo [ c, e ] [1,2] oxathiane-6-oxide compound | 中国科学院成都生物研究所 | 2020-01-14 | — | — | CN | disclosed |