Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400986 | 0.84 | HPGD (0.50) | HPGDKDM4ENPC1RAB9ACA2 | |
| SCHEMBL28888486 | 0.82 | L3MBTL1 (0.45) | KMT2AKDM4EALDH1A1LMNATP53 | |
| SCHEMBL28393540 | 0.82 | KMT2A (0.55) | HPGDKMT2ARXFP1ALDH1A1USP2 | |
| SCHEMBL28394273 | 0.81 | MAPT (0.46) | KMT2AALDH1A1USP2HSD17B10TP53 | |
| SCHEMBL28394262 | 0.80 | L3MBTL1 (0.43) | HPGDKMT2ARXFP1KDM4ERAB9A | |
| SCHEMBL28397524 | 0.80 | ALDH1A1 (0.46) | HPGDKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL28394808 | 0.80 | GAA (0.51) | HPGDKMT2ARXFP1KDM4ECA2 | |
| SCHEMBL28888853 | 0.80 | L3MBTL1 (0.60) | KMT2AKDM4ERAB9AALDH1A1USP2 | |
| SCHEMBL28393810 | 0.80 | MEN1 (0.50) | KMT2AALDH1A1LMNATP53TSHR | |
| SCHEMBL28345475 | 0.75 | CA2 (0.51) | HPGDKMT2AKDM4ECA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | claimed |
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |