Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28394808 | 0.89 | GAA (0.51) | L3MBTL1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL28888486 | 0.89 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL28397524 | 0.89 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL28393540 | 0.89 | KMT2A (0.55) | ALDH1A1KMT2AMEN1POLBNR4A1 | |
| SCHEMBL28393014 | 0.88 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL28888853 | 0.86 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL28401000 | 0.86 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL28396249 | 0.83 | MAPT (0.56) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL28348405 | 0.80 | HRH4 (0.47) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL28400986 | 0.80 | HPGD (0.50) | L3MBTL1ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822126-B | Thienopyran formyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-05-15 | — | — | CN | claimed |
| CN-108822126-B | Thienopyran formyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-05-15 | — | — | CN | disclosed |