Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397526 | 0.84 | ALDH1A1 (0.49) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL28346207 | 0.82 | ALDH1A1 (0.52) | KMT2ANPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL28348392 | 0.81 | HRH4 (0.48) | KMT2AALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28348687 | 0.80 | MAOB (0.50) | MAOBKMT2ANPSR1MAPTALDH1A1 | |
| SCHEMBL28396618 | 0.79 | SMN1; SMN2 (0.51) | KMT2ANPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL28400024 | 0.77 | LMNA (0.43) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL28391828 | 0.76 | KMT2A (0.50) | KMT2ANPSR1MAPTALDH1A1MEN1 | |
| SCHEMBL28401171 | 0.76 | LMNA (0.45) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL28405211 | 0.76 | ADAMTS5 (0.43) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL16599230 | 0.74 | HRH4 (0.67) | MAOBKMT2ANPSR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | claimed |
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |