Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345520 | 0.88 | LSS (0.46) | ALDH1A1LMNAHTTTSHRMAPK1 | |
| SCHEMBL28345522 | 0.84 | BCL2 (0.42) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28397526 | 0.84 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTTSHRMAPK1 | |
| SCHEMBL28348407 | 0.82 | MAOB (0.47) | ALDH1A1LMNAHTTTSHRMAPT | |
| SCHEMBL28348392 | 0.81 | HRH4 (0.48) | ALDH1A1LMNATSHRKMT2AL3MBTL1 | |
| SCHEMBL28396618 | 0.79 | SMN1; SMN2 (0.51) | ALDH1A1TSHRMAPK1MAPTNPSR1 | |
| SCHEMBL28401171 | 0.78 | LMNA (0.45) | ALDH1A1LMNAHTTTSHRMAPK1 | |
| SCHEMBL28400024 | 0.77 | LMNA (0.43) | ALDH1A1LMNAHTTTSHRMAPT | |
| SCHEMBL28391828 | 0.76 | KMT2A (0.50) | ALDH1A1LMNAHTTTSHRMAPK1 | |
| SCHEMBL28348917 | 0.73 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | claimed |
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |