Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 12/20 | 0.60 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889686 | 1.00 | FPR2 (0.60) | FPR2CTSSCTSKCTSBCTSL | |
| SCHEMBL14902575 | 0.91 | FPR2 (0.63) | FPR2CTSSCTSKCTSBCTSL | |
| SCHEMBL28352113 | 0.91 | FPR2 (0.63) | FPR2CTSSCTSKCTSBCTSL | |
| SCHEMBL22175320 | 0.85 | CTSS (0.46) | FPR2CTSSCTSKCTSBCTSL | |
| SCHEMBL14889868 | 0.85 | FPR2 (0.70) | FPR2TACR2MEN1NPC1RAB9A | |
| SCHEMBL20484373 | 0.85 | FPR2 (0.70) | FPR2TACR2MEN1NPC1RAB9A | |
| SCHEMBL14902624 | 0.83 | FPR2 (0.70) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL28348563 | 0.83 | FPR2 (0.70) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22150325 | 0.83 | FPR2 (0.70) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14889720 | 0.82 | FPR2 (0.71) | FPR2TACR2MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518742-B | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2020-01-21 | — | — | CN | claimed |
| CN-106518742-B | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2020-01-21 | — | — | CN | disclosed |