Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.50 |
| ▸ | PNP | P00491 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TK1 | P04183 | 2/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27562476 | 0.91 | XDH (0.42) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL6755679 | 0.90 | XDH (0.41) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL986800 | 0.85 | XDH (0.60) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL15005119 | 0.83 | XDH (0.59) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL3953063 | 0.82 | XDH (0.38) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL9241289 | 0.76 | XDH (0.50) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL1825531 | 0.75 | XDH (0.51) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL10835122 | 0.75 | XDH (0.61) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL72147 | 0.74 | XDH (0.50) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL1831279 | 0.74 | XDH (0.50) | XDHPNPBLMUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858949-A | RNAi agents for inhibiting expression of mucin 5AC (MUC 5 AC), compositions thereof, and methods of use thereof | 箭头药业股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-110740994-A | Peptide Nucleic Acid (PNA) monomers with orthogonally protected ester moieties | 特鲁科德基因修复公司 | 2020-01-31 | — | — | CN | disclosed |