Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.41 |
| ▸ | PNP | P00491 | 4/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 2/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348671 | 0.90 | XDH (0.50) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL1825531 | 0.86 | XDH (0.51) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL27562476 | 0.84 | XDH (0.42) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL3953063 | 0.76 | XDH (0.38) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL986800 | 0.75 | XDH (0.60) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL28695644 | 0.75 | XDH (0.43) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL15005119 | 0.74 | XDH (0.59) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL556881 | 0.73 | XDH (0.50) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL27983442 | 0.72 | CDK1 (0.59) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL1831279 | 0.71 | XDH (0.50) | XDHPNPBLMUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527207-A | GalNAc derivatives | 詹森生物制药有限公司 | 2020-08-11 | — | — | CN | disclosed |
| WO-2004053168-A1 | MODULATION OF ADIPOPHILIN EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2004-06-24 | — | — | WO | disclosed |