Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352943 | 0.87 | RORC (0.61) | RORCCA1CA2ALDH1A1GAA | |
| SCHEMBL30531889 | 0.87 | RORC (0.61) | RORCCA1CA2ALDH1A1GAA | |
| SCHEMBL28352398 | 0.86 | RORC (0.61) | RORCCA1CA2ALDH1A1GAA | |
| SCHEMBL29488705 | 0.83 | RORC (0.71) | RORCCA1CA2ALDH1A1POLB | |
| SCHEMBL30531891 | 0.81 | ALDH1A1 (0.55) | RORCALDH1A1 | |
| SCHEMBL28349310 | 0.81 | ALDH1A1 (0.55) | RORCALDH1A1 | |
| SCHEMBL23224423 | 0.78 | LOX (0.54) | CA1CA2ALDH1A1GAAPOLB | |
| SCHEMBL7235420 | 0.77 | LMNA (0.65) | ALDH1A1MMP13 | |
| SCHEMBL3029989 | 0.76 | CFD (0.69) | ALDH1A1GAAHSD17B10MMP13POLB | |
| SCHEMBL10789252 | 0.76 | SMN1; SMN2 (0.56) | GAAHSD17B10MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024319-A | Amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-110724075-B | Amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-110724075-A | Amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-01-24 | — | — | CN | disclosed |