Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942798 | 0.85 | DGKA (0.61) | CYP1A2DGKAPAMLMNAKDM4E | |
| Sulfuric Acid SCHEMBL6368814 | 0.82 | DGKA (0.64) | CYP1A2DGKAPAMLMNAKDM4E | |
| Sulfuric Acid SCHEMBL7924258 | 0.82 | DGKA (0.64) | CYP1A2DGKAPAMLMNAKDM4E | |
| Monoethanolamine SCHEMBL5498813 | 0.81 | DGKA (0.46) | DGKAPAMLMNAKDM4EDUSP3 | |
| Sulfuric Acid SCHEMBL9776635 | 0.81 | DGKA (0.62) | CYP1A2DGKAPAMLMNAKDM4E | |
| Sulfuric Acid SCHEMBL28105327 | 0.81 | DGKA (0.62) | CYP1A2DGKAPAMLMNAKDM4E | |
| Octadecylamine SCHEMBL7643247 | 0.81 | CYP1A2 (0.74) | CYP1A2DGKAPAMLMNAKDM4E | |
| Ethyl Tetradecanoate SCHEMBL31277626 | 0.81 | DGKA (0.62) | CYP1A2DGKAPAMLMNAKDM4E | |
| Sulfuric Acid SCHEMBL669289 | 0.81 | DGKA (0.62) | CYP1A2DGKAPAMLMNAKDM4E | |
| Ethyl Oleate SCHEMBL6072559 | 0.81 | ALDH1A1 (0.61) | CYP1A2DGKAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471543-A | Close-fitting clothes washing gel bead and preparation method thereof | 福建恒安集团有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-110725127-A | Fabric softener | 广州英锘科化工有限公司 | 2020-01-24 | — | — | CN | disclosed |