Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ethyl Oleate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | DGKA | P23743 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 3/20 | 0.59 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 2/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
| ▸ | PRKCA | P17252 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Oleate SCHEMBL28248089 | 0.92 | ALDH1A1 (0.63) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| Ethyl Oleate SCHEMBL27479328 | 0.92 | ALDH1A1 (0.63) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| Dectaflur SCHEMBL22689506 | 0.92 | ALDH1A1 (0.63) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| Ethyl Oleate SCHEMBL28098991 | 0.91 | ALOX15 (0.65) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| Ethyl Oleate SCHEMBL17443164 | 0.91 | ALOX15 (0.65) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| Ethyl Oleate SCHEMBL6369777 | 0.91 | ALOX15 (0.69) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| Ethyl Oleate SCHEMBL6369771 | 0.91 | ALOX15 (0.69) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL25490302 | 0.91 | HSD17B10 (0.73) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL588560 | 0.91 | HSD17B10 (0.73) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| Ethyl Oleate SCHEMBL1896892 | 0.91 | HSD17B10 (0.73) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891203-A | OIL ADDITIVE FOR LOW SULFUR FUELS | ETHYL CORPORATION (US) | 1999-04-06 | — | — | US | claimed |
| US-20060196111-A1 | Fuel additive composition | AFTON CHEMICAL CORPORATION | 2006-09-07 | — | — | US | disclosed |
| US-5891203-A | OIL ADDITIVE FOR LOW SULFUR FUELS | ETHYL CORPORATION (US) | 1999-04-06 | — | — | US | disclosed |
| US-4208293-A | Improved crankcase lubricant composition | ETHYL CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4204481-A | A MONOHYDROXY ALCOHOL AND A FATTY ACID AMIDE OR DIETHANOLAMINE | ETHYL CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |