Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 12/20 | 0.77 |
| ▸ | KDR | P35968 | 6/20 | 0.73 |
| ▸ | AURKA | O14965 | 3/20 | 0.71 |
| ▸ | EGFR | P00533 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28354676 | 0.89 | SRC (0.77) | SRCKDRAURKAEGFR | |
| SCHEMBL28882352 | 0.89 | SRC (0.77) | SRCKDRAURKAEGFR | |
| SCHEMBL28354714 | 0.88 | SRC (0.73) | SRCKDRAURKAEGFR | |
| SCHEMBL28350757 | 0.88 | SRC (0.73) | SRCKDRAURKAEGFR | |
| SCHEMBL13529060 | 0.88 | SRC (0.84) | SRCKDRAURKAEGFR | |
| SCHEMBL28350781 | 0.87 | EGFR (0.76) | SRCKDREGFR | |
| SCHEMBL28350501 | 0.87 | EGFR (0.76) | SRCKDREGFR | |
| SCHEMBL14216857 | 0.86 | SRC (0.70) | SRCKDRAURKAEGFRKDM4E | |
| SCHEMBL28354308 | 0.86 | SRC (0.77) | SRCKDRAURKAEGFR | |
| SCHEMBL28350517 | 0.86 | SRC (0.77) | SRCKDRAURKAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746398-A | 4-heterocyclic substituted quinazoline derivative and preparation method and application thereof | 刘沛友 | 2020-02-04 | — | — | CN | disclosed |