Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24059038 | 0.98 | — | — | |
| SCHEMBL24052008 | 0.91 | INMT (0.30) | INMTBRD4BRD2 | |
| Hydrochloric Acid SCHEMBL18244803 | 0.89 | — | — | |
| Water SCHEMBL357691 | 0.81 | — | — | |
| Iodide SCHEMBL7223430 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL28535074 | 0.81 | — | — | |
| SCHEMBL19461025 | 0.76 | — | — | |
| SCHEMBL598307 | 0.71 | — | — | |
| SCHEMBL1897945 | 0.67 | — | — | |
| SCHEMBL2866921 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11269149-A | — | — | None | — | — | JP | disclosed |
| JP-6234725-A | — | — | None | — | — | JP | disclosed |
| JP-4308547-A | — | — | None | — | — | JP | disclosed |
| JP-5097714-A | — | — | None | — | — | JP | disclosed |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| EP-4153747-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | Wave Life Sciences Ltd. (SG) | 2023-03-29 | — | — | EP | disclosed |
| EP-4153604-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2023-03-29 | — | — | EP | disclosed |
| WO-2021234459-A9 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2022-02-03 | — | — | WO | disclosed |
| WO-2021237223-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| JP-H11269149-A | PRODUCTION OF 2-IMINOIMIDAZOLIDINES | SHIRATORI SEIYAKU KK | 1999-10-05 | — | — | JP | disclosed |
| US-5892061-A | REACTING A MONO- OR POLYCARBOXYLIC ACID WITH A MONO- OR POLYAMIDE IN THE PRESENCE OF A HALOIMINIUM SALT AND BASE; CATALYST SELECTIVITY | MITSUI CHEMICALS, INC. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0846714-A1 | Preparation process of isoimide | Mitsui Chemicals, Inc. (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5750779-A | Preparation process of acyl halide or sulfonyl halide | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5719256-A | CONDENSING CARBOXYL GROUP CONTAINING COMPOUND AND ACTIVE HYDROGEN CONTAINING COMPOUND IN PRESENCE OF HALOIMINIUM SALT AS POLYMERIZATION CATALYST | MITSU TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0769512-A2 | Process for preparing polycondensation polymers | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-04-23 | — | — | EP | disclosed |
| EP-0751131-A1 | A process for preparing an acyl halide or sulfonyl halide | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-01-02 | — | — | EP | disclosed |
| JP-H06234725-A | PRODUCTION OF CARBODIIMIDES | SHIRATORI SEIYAKU KK | 1994-08-23 | — | — | JP | disclosed |
| JP-H0597714-A | PRODUCTION OF NITRILES | SHIRATORI SEIYAKU KK | 1993-04-20 | — | — | JP | disclosed |
| JP-H04308547-A | PRODUCTION OF 3-HALOGENO-2,3-UNSATURATED KETONE | SHIRATORI SEIYAKU KK | 1992-10-30 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | RNGTT, NSUN2, ALKBH1 | INMT 164/4885BRD4 4531/4885BRD2 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.