Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352194 | 0.86 | ALDH1A1 (0.41) | ADAMTS5ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28352077 | 0.84 | ALDH1A1 (0.38) | ADAMTS5EGLN1ALDH1A1KDM4ELMNA | |
| SCHEMBL30972506 | 0.70 | RAD52 (0.48) | ADAMTS5ALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL7613143 | 0.70 | ALDH1A1 (0.48) | ADAMTS5EGLN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4223414 | 0.68 | P2RX4 (0.41) | ALDH1A1 | |
| SCHEMBL7372104 | 0.68 | PGR (0.65) | ADAMTS5EGLN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12997888 | 0.68 | PGR (0.65) | ADAMTS5EGLN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30881981 | 0.68 | PGR (0.65) | ADAMTS5EGLN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22921215 | 0.67 | ALDH1A1 (0.44) | ADAMTS5EGLN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11030756 | 0.66 | LMNA (0.44) | EGLN1ALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997183-B | Difluoromethylation reagent and preparation method and application thereof | 深圳大学 | 2020-02-07 | — | — | CN | disclosed |