Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446346 | 0.81 | GABRA1 (0.37) | TSHRTDP1ALDH1A1CES1KDM4E | |
| SCHEMBL19283984 | 0.80 | ALDH1A1 (0.42) | TSHRTDP1ALDH1A1CES1KDM4E | |
| SCHEMBL8308824 | 0.80 | EDNRB (0.45) | ALDH1A1KIF11CES1KCNN4MAPT | |
| SCHEMBL6120771 | 0.77 | ALDH1A1 (0.51) | TDP1ALDH1A1KIF11KDM4EHPGD | |
| SCHEMBL2723142 | 0.77 | ALDH1A1 (0.51) | TDP1ALDH1A1KIF11KDM4EHPGD | |
| SCHEMBL29697583 | 0.77 | ALDH1A1 (0.51) | TDP1ALDH1A1KIF11KDM4EHPGD | |
| SCHEMBL29649169 | 0.77 | ALDH1A1 (0.51) | TDP1ALDH1A1KIF11KDM4EHPGD | |
| SCHEMBL12940368 | 0.77 | ALDH1A1 (0.51) | TDP1ALDH1A1KIF11KDM4EHPGD | |
| SCHEMBL29697568 | 0.77 | ALDH1A1 (0.51) | TDP1ALDH1A1KIF11KDM4EHPGD | |
| SCHEMBL5046100 | 0.76 | KCNN4 (0.50) | TSHRTDP1ALDH1A1CES1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110613705-A | Application of tetrahydrocurcumin in preparation of medicine for treating breast cancer or/and preventing breast cancer metastasis | 四川省中医药科学院 | 2019-12-27 | — | — | CN | disclosed |