Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29649169 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL29697583 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL29697568 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL6120771 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL12940368 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| Mandelic Acid SCHEMBL16689936 | 0.89 | LMNA (0.47) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL9088372 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL9087816 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL9551660 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL7945062 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148783-A4 | CONVERTING COX INHIBITION COMPOUNDS THAT ARE NOT COX-2 SELECTIVE INHIBITORS TO DERIVATIVES THAT ARE COX-2 SELECTIVE INHIBITORS | UNIV VANDERBILT (US) | 2003-05-21 | — | — | EP | claimed |
| EP-1148783-A1 | CONVERTING COX INHIBITION COMPOUNDS THAT ARE NOT COX-2 SELECTIVE INHIBITORS TO DERIVATIVES THAT ARE COX-2 SELECTIVE INHIBITORS | Vanderbilt University (US) | 2001-10-31 | — | — | EP | claimed |
| WO-2000040087-A1 | CONVERTING COX INHIBITION COMPOUNDS THAT ARE NOT COX-2 SELECTIVE INHIBITORS TO DERIVATIVES THAT ARE COX-2 SELECTIVE INHIBITORS | VANDERBILT UNIVERSITY (US) | 2000-07-13 | — | — | WO | claimed |
| EP-0380316-A2 | Preparation of alpha-methylareneacetic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1990-08-01 | — | — | EP | claimed |
| US-20240329525-A1 | PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-10-03 | — | — | US | disclosed |
| US-20240210827-A1 | PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-06-27 | — | — | US | disclosed |
| EP-4347836-A2 | COMPOSITIONS AND METHODS FOR SILENCING CARBONIC ANHYDRASE 2 EXPRESSION | Alnylam Pharmaceuticals, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-113820920-B | Photosensitive resin composition, method for producing cured relief pattern, and semiconductor device | 旭化成株式会社 | 2023-07-04 | — | — | CN | disclosed |
| US-11613551-B2 | Aminoglycoside derivatives and uses thereof in treating genetic disorders | ELOXX PHARMACEUTICALS LTD. (IL) | 2023-03-28 | — | — | US | disclosed |
| CN-110088680-B | Double-layer photosensitive layer roll | 旭化成株式会社 | 2022-12-30 | — | — | CN | disclosed |
| CN-115185157-A | Photosensitive resin composition, method for producing cured relief pattern, and semiconductor device | 旭化成株式会社 | 2022-10-14 | — | — | CN | disclosed |
| CN-114957357-A | Aminoglycoside derivatives and their use in the treatment of genetic disorders | ELOXX制药有限公司 | 2022-08-30 | — | — | CN | disclosed |
| US-6407135-B1 | NITRIC OXIDE SCAVENGER COVALENTLY BONDED TO NON-STEROIDAL ANTIINFLAMMATORY AGENT OR OTHER DRUG; SIDE EFFECT REDUCTION | MEDINOX, INC. | 2002-06-18 | — | — | US | disclosed |
| WO-2001062085-A1 | PROTECTED FORMS OF PHARMACOLOGICALLY ACTIVE AGENTS AND USES THEREFOR | MEDINOX, INC. (US) | 2001-08-30 | — | — | WO | disclosed |
| US-6274627-B1 | ADMINISTERING COMPOUNDS SUCH AS N-METHYL-D-GLUCAMINE DITHIO-CARBAMATE DISULFIDE FOR IN VIVO REDUCTION OF FREE RADICAL LEVELS IN A SUBJECT | MEDINOX, INC. | 2001-08-14 | — | — | US | disclosed |
| WO-1996025152-A1 | PROCESS OF PREPARING THERAPEUTIC COMPOSITIONS CONTAINING NANOPARTICLES | NANOSYSTEMS L.L.C. (US) | 1996-08-22 | — | — | WO | disclosed |
| US-4672077-A | Novel soluble salt having analgesic and anti-inflammatory activity, a process for the preparation thereof and pharmaceutical forms containing them | ISTITUTO BIOCHIMICO PAVESE SPA (IT) | 1987-06-09 | — | — | US | disclosed |
| US-4565877-A | Naphthalene derivatives and method for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1986-01-21 | — | — | US | disclosed |
| EP-0107149-B1 | NOVEL NAPHTHALENE DERIVATIVES AND METHOD FOR PREPARATION THEREOF | Tanabe Seiyaku Co., Ltd. (JP) | 1985-10-16 | — | — | EP | disclosed |
| EP-0107149-A1 | Novel naphthalene derivatives and method for preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1984-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11613551-B2 | Aminoglycoside derivatives and uses thereof in treating genetic disorders | UPF1, AARS1, NUDT21 | ALDH1A1 1473/4885KDM4E 2974/4885HSD17B10 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.