Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724400 | 0.88 | BCAT2 (0.44) | KMT2APOLBEGFR | |
| SCHEMBL3556748 | 0.84 | FOLH1 (0.54) | SRD5A2KMT2AFOLH1RXRARXRB | |
| SCHEMBL3588665 | 0.82 | TTR (0.50) | TTRALDH1A1PTPRCSRD5A2KMT2A | |
| SCHEMBL2635961 | 0.80 | BCL2 (0.50) | TTRALDH1A1PTPRCSRD5A2KMT2A | |
| SCHEMBL27650074 | 0.79 | TTR (0.47) | TTRALDH1A1PTPRCSRD5A2KMT2A | |
| SCHEMBL28393638 | 0.79 | ALOX5 (0.53) | ALDH1A1KMT2A | |
| SCHEMBL6310172 | 0.79 | TTR (0.47) | TTRALDH1A1PTPRCSRD5A2KMT2A | |
| SCHEMBL16056461 | 0.78 | FOLH1 (0.62) | ALDH1A1KMT2AFOLH1 | |
| SCHEMBL13385994 | 0.77 | LMNA (0.44) | ALDH1A1KMT2A | |
| SCHEMBL29018975 | 0.77 | MMP3 (0.44) | ALDH1A1KMT2AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406451-B | Pyrrolopyrimidines and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | 福马治疗股份有限公司 | 2019-12-17 | — | — | CN | disclosed |